MPN: CG681-S6093
MSI CG681-S6093
6U · 8× 1,200 W GPUs · Dual EPYC SP7

MSI’s liquid-cooled 6U AI server plus the full NVIDIA MGX, DC-MHS multi-node and Open Compute portfolio · AMD EPYC SP7/SP8 · forward path to Vera Rubin rack-scale

CG681-S6093

MSI’s headline 6U liquid-cooled AI server, shown at COMPUTEX 2026.

MGX GPU platforms (4U / 2U)

NVIDIA MGX-based systems covering multiple GPU generations for AI training, inference and HPC.

DC-MHS core compute

Open Compute multi-node platforms for cloud and service-provider density.

G4101-01 4U GPU server

Liquid-cooled 4-GPU platform on a single AMD EPYC 9004 processor.

Specifications

Vendor

MSI (Micro-Star International)

Product

CG681-S6093 / MGX 4U & 2U / DC-MHS / G4101-01

Type

Rack-mount AI GPU servers & multi-node platforms

Headline System

CG681-S6093
6U liquid-cooled GPU server

CPU Support

Dual AMD EPYC SP7 (up to 256C/512T)
Dual AMD EPYC SP8 (up to 128C/256T)

GPU Support

Up to 8 × RTX PRO 6000 Blackwell Server Edition
H200 NVL / RTX PRO 4500 Blackwell SE

Max GPU TDP

Up to 1,200 W per GPU

Architecture

NVIDIA MGX
OCP DC-MHS

Form Factors

6U, 4U, 2U GPU servers
2U4N / 2U2N multi-node

Open Compute

21-inch chassis, 48V DC busbar

Multi-node Model

CD270-S4091-X2

4U Platform

G4101-01, single AMD EPYC 9004

Networking Target

AI training, inference, HPC, data-intensive workloads

Roadmap

Next-generation NVIDIA Vera Rubin rack-scale systems

Announced

COMPUTEX 2026 · AMD Advancing AI 2026

Price

Quote

Overview

MSI has moved well beyond gaming hardware into full-spectrum AI infrastructure. Its Enterprise Platform Solutions division now spans GPU servers, DC-MHS multi-node compute, OCP open-compute chassis, enterprise and mainstream servers, deskside AI workstations and server motherboards — a portfolio aimed at the same tier-1 datacenter accounts as Dell, Supermicro and Aivres.

The rack-scale headline is the CG681-S6093, a 6U liquid-cooled GPU server carrying dual AMD EPYC SP7 processors with up to 256 cores / 512 threads each and supporting up to eight NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs at up to 1,200 W TDP. Alongside it, MSI’s NVIDIA MGX portfolio covers 4U and 2U GPU platforms supporting H200 NVL, RTX PRO 6000 and RTX PRO 4500 Blackwell Server Edition parts across AI training, inference, HPC and data-intensive workloads, with a stated forward path into next-generation Vera Rubin rack-scale systems. For cloud and service-provider density, MSI pairs OCP DC-MHS architecture with 19-inch chassis in 2U4N (density) and 2U2N (efficiency) configurations, plus 21-inch Open Compute chassis using a 48V DC busbar; the CD270-S4091-X2 multi-node server was demonstrated at AMD Advancing AI 2026. At 4U, the G4101-01 delivers a liquid-cooled four-GPU platform on a single AMD EPYC 9004 processor with 80 PLUS Titanium or Platinum power.

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