5 Variants: MI455X · MI450 · MI440X · MI430X · MI400X | 320B Transistors · 19.6 TB/s · UALink Open Interconnect
Instinct MI455X
AMD CDNA 5
TSMC N2 (2nm)
320 Billion
432 GB HBM4
19.6 TB/s
40 PFLOPs
20 PFLOPs
12× N2 Compute
+ 3× N3 Advanced
300 GB/s per GPU
UALink (Open Standard)
Infinity Fabric
OAM Module
Liquid Cooling
PCIe Gen 6
Full-chip HBM4
Yes
H1 2026
H2 2026
$7.2 Billion
| Specification | AMD MI455X | NVIDIA B200 | NVIDIA B300 |
|---|---|---|---|
| Architecture | CDNA 5 | Blackwell | Blackwell Ultra |
| Process Node | TSMC N2 (2nm) | TSMC 4NP | TSMC 4NP |
| Memory | 432 GB HBM4 | 192 GB HBM3e | 288 GB HBM3e |
| Bandwidth | 19.6 TB/s | 8 TB/s | 12 TB/s |
| FP4 | 40 PFLOPS | ~40 PFLOPS | ~50 PFLOPS |
| FP8 | 20 PFLOPS | ~20 PFLOPS | ~25 PFLOPS |
| Transistors | 320 billion | 208 billion | 208 billion |
| Interconnect | UALink (open) | NVLink (prop.) | NVLink (prop.) |
AMD's Helios platform is the MI400's answer to NVIDIA DGX systems. A single Helios rack houses 72 MI455X GPUs paired with EPYC "Venice" (Zen 6) CPUs, delivering:
AMD's first-year MI400 revenue is projected at $7.2 billion, with the data center GPU business forecast to generate $15 billion in 2026 — 114% YoY growth. Major cloud partners include TensorWave, with OpenAI, Meta, and Anthropic among early demand drivers.
The MI400 series is AMD's first GPU on TSMC N2 (2nm), representing a full node shrink from MI350's 3nm/6nm process. The MI455X packs 320 billion transistors across a multi-chiplet design — 12 compute chiplets on N2 plus 3 advanced chiplets on 3nm. HBM4 memory delivers 2.4× the bandwidth of MI350's HBM3E, making the MI400 a transformative upgrade for memory-bound large language model workloads.
All MI400 GPUs support UALink, the open interconnect standard backed by AMD, Intel, Google, Meta, and Microsoft — a direct challenge to NVIDIA's proprietary NVLink ecosystem. Combined with AMD's open-source ROCm 6 software stack, the MI400 series offers enterprises a credible alternative to NVIDIA for large-scale AI infrastructure.
QS Compute can source AMD Instinct MI400 series GPUs and Helios rack-scale systems for enterprise and hyperscale deployments across APAC. Contact us for pre-order, cluster pricing, and integration services.
Need AMD Instinct MI400 Series?
Next-gen CDNA 5 architecture with 432GB HBM4. Available for pre-order — contact us for cluster pricing and deployment timelines.
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