Advantech MIO-5381 — 3.5″ SBC on Intel Core Ultra Series 3 with USB4 and MCIO

Specifications

Overview

The Advantech MIO-5381 is the USB4-generation 3.5-inch board in Advantech's MI/O-Compact line, built on Intel Core Ultra Series 3. It supports up to 14 cores at a 28 W TDP and dual-channel DDR5-7200 to 128 GB with in-band ECC, which matters for inference workloads where a single undetected memory error corrupts a result.

Two mezzanine options define the board. MIOe-TCPD adds USB Type-C power delivery up to 100 W, allowing the SBC itself to be powered and to deliver power over the same cable; MIOe-UMXM routes USB4 out to an external discrete GPU, so a graphics or accelerator card can be added without redesigning the carrier. MCIO carries PCIe Gen4 x4 signalling out to a standard PCIe slot for NVMe or NIC add-in cards.

Combined with 4 UARTs and 2 CAN channels, the MIO-5381 covers the control-side I/O of an industrial node while leaving headroom for accelerator expansion — a configuration that suits vision gateways, medical devices and robotics controllers.

Key Benefits

IBECC DDR5-7200 to 128 GB for error-checked inference memory. USB4 and MCIO PCIe Gen4 x4 provide two independent high-bandwidth expansion paths. MIOe-TCPD / MIOe-UMXM mezzanines add 100 W USB-C power delivery or an external discrete GPU. -40 to 85 °C extended-temperature option for outdoor and vehicle deployments.

Applications

Vision gateways and AI inspection nodes, robotics and AGV controllers, medical imaging front ends, and industrial edge systems that need error-checked memory plus an accelerator expansion path.

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